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Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and Chronic Leishmania donovani Infection in BALB/c Mice

机译：葡萄糖酸锑酸钠联合含硬脂酰胺的脂质体联合治疗BALB / c小鼠已建立的慢性利什曼原虫的感染

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In this work we report the activity seen with combination therapy using sodium antimony gluconate in liposomes composed of egg phosphatidyl choline and stearylamine for elimination of Leishmania donovani parasites from the liver and spleen of BALB/c mice with established and chronic infections.

机译：在这项工作中，我们报告了在含有卵磷脂酰胆碱和硬脂胺的脂质体中使用葡萄糖酸锑酸钠联合治疗所产生的活性，以消除患有已确定和慢性感染的BALB / c小鼠的肝脏和脾脏中的利什曼原虫。

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Pal, Swati; Ravindran, Rajesh; Ali, Nahid;
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年度 2004
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专利

1. Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and Chronic Leishmania donovani Infection in BALB/c Mice. [J] . Pal S, Ravindran R, Ali N Antimicrobial agents and chemotherapy. . 2004,第9期

机译：在携带硬脂胺的脂质体中使用葡糖酸锑酸钠联合治疗BALB / c小鼠中已建立的慢性利什曼原虫的感染。
2. Sub-optimal dose of Sodium Antimony Gluconate (SAG)-diperoxovanadate combination clears organ parasites from BALB/c mice infected with antimony resistant Leishmania donovani by expanding antileishmanial T-cell repertoire and increasing IFN-gamma to IL-10 ratio [J] . Haldar AK, Banerjee S, Naskar K, Experimental parasitology . 2009,第2期

机译：亚最佳剂量的葡萄糖酸钠（SAG）-二过氧钒酸盐组合物通过扩大抗疟原虫T细胞库并增加IFN-γ与IL-10的比例来清除感染锑抗性利什曼原虫的BALB / c小鼠的器官寄生虫
3. Depletion of interleukin-4 in BALB/c mice with established Leishmania major infections increases the efficacy of antimony therapy and promotes Th1-like responses. [J] . G S Nabors, J P Farrell Infection and immunity . 1994,第12期

机译：在已建立的利什曼原虫主要感染的BALB / c小鼠中，白细胞介素4的消耗增加了锑治疗的功效并促进了Th1样反应。
4. Targeted photodynamic therapy of established soft-tissue infections in mice [C] . Faten Gad, Touqir Zahra, Tayyaba Hasan, Conference on optical methods for tumor treatment and detection: Mechanisms and techniques in photodynamic therapy . 2004

机译：针对小鼠建立的软组织感染的有针对性的光动力学治疗
5. Studies on the Chemotherapy of Leishmania donovani Infections Using Compounds That Affect Trypanothione Metabolism [D] . Matara, Chrysanthi C. 1991

机译：影响锥虫新陈代谢的化合物对多谢利什曼原虫感染的化学治疗研究
6. Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and Chronic Leishmania donovani Infection in BALB/c Mice [O] . Swati Pal, Rajesh Ravindran, Nahid Ali 2004

机译：葡萄糖酸锑酸钠联合含硬脂胺的脂质体联合治疗BALB / c小鼠已建立的慢性利什曼原虫感染的组合疗法
7. Therapy with Sodium Stibogluconate in Stearylamine-Bearing Liposomes Confers Cure against SSG-Resistant Leishmania donovani in BALB/c Mice [O] . Roychoudhury, Jayeeta, Sinha, Roma, Ali, Nahid 2011

机译：含硬脂酰胺的脂质体中糖基葡萄糖酸钠的治疗可治愈BALB / c小鼠中抗SSG的利什曼原虫donovani
8. Randomized Controlled Trial of Local Heat Therapy Versus Intravenous Sodium Stibogluconate for the Treatment of Cutaneous Leishmania Major Infection [R] . Aronson, N. E., Wortmann, G. W., Byrne, W. R., 2010

机译：局部热疗与静脉注射葡萄糖酸钠治疗皮肤利什曼原虫感染的随机对照试验

Combination Therapy Using Sodium Antimony Gluconate in Stearylamine-Bearing Liposomes against Established and Chronic Leishmania donovani Infection in BALB/c Mice

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